Open Position

Developing high-throughput methods for Spatial Transcriptomics and Multi-Omics

Are you interested to work at the intersection of biology, engineering, and computational biology?

In the lab of  Matthias Meier at the Helmholtz Pioneer Campus, we are looking for a motivated intern or Master student to develop novel Spatial Transcriptomics methods.

Spatial Transcriptomics enables mapping of all mRNAs in biological samples to study disease states in complex tissues. This project will focus on further developing the method, increasing resolution, sensitivity and throughput, and expanding its scope to multiple organs.

The spectrum of methods that you can learn spans both seminal and established research fields:

  • Spatial Transcriptomics using microfluidic device
  • Computational analysis using Scanpy (Python)
  • Next Generation Sequencing
  • Molecular biological methods (In situ reverse transcription, PCR, NGS library preparation)
  • 3D-printing
  • Design of microfluidic chips using Solidworks
  • Microfluidic chip production using soft lithography
  • Cryosectioning

Requirements:

  • Bachelor degree in Biology/Biochemistry/Bioengineering.
  • Good skills in biological wet lab work.
  • Motivation and analytical skills to work independently on your own research question.
  • Basic programming skills beneficial but not needed (preferably Python). General interest in learning a programming language required.

Starting Date: 

  • As soon as possible.

Contact:

For further details, please contact Johannes Wirth (Johannes.wirthnoSp@m@helmholtz-muenchen.de; Meier Lab, Helmholtz Pioneer Campus, Helmholtz Zentrum München)