1. About
  2. Principal Investigators
  3. Celia P. Martinez-Jimenez
  4. All publications
2020
Kamies, R. ; Martinez Jimenez, C.P.
Advances of single-cell genomics and epigenomics in human disease: Where are we now?
Mamm. Genome 31, 170-180 (2020)
2019
Chen, H.C. ; Eling, N. ; Martinez Jimenez, C.P. ; O'Brien, L.M. ; Carbonaro, V. ; Marioni, J.C. ; Odom, D.T. ; de la Roche, M.
IL-7-dependent compositional changes within the gamma delta T cell pool in lymph nodes during ageing lead to an unbalanced anti-tumour response.
EMBO Rep. 20:e47379 (2019)
2018
Chen, H.-C ; Eling, N. ; Martinez Jimenez, C.P. ; O'Brien, L.M. ; Marioni, J.C. ; Odom, D.T. ; de la Roche, M.
Altered composition of the γδ T cell pool in lymph nodes during ageing enhances tumour growth.
bioRxiv, DOI: 10.1101/480327 (2018)
Ernst, C. ; Eling, N. ; Martinez Jimenez, C.P. ; Marioni, J.C. ; Odom, D.T.
Staged developmental mapping and X chromosome transcriptional dynamics during mouse spermatogenesis.
Nat. Commun. 10:1251 (2018)
2017
Martinez Jimenez, C.P. ; Eling, N. ; Chen, H.-C ; Vallejos, C.A. ; Kolodziejczyk, A.A. ; Connor, F. ; Stojic, L. ; Rayner, T.F. ; Stubbington, M.J.T. ; Teichmann, S.A. ; de la Roche, M. ; Marioni, J.C. ; Odom, D.T.
Aging increases cell-to-cell transcriptional variability upon immune stimulation.
Science 355, 1433-1436 (2017)
Le Guével, R. ; Oger, F. ; Martinez Jimenez, C.P. ; Bizot, M. ; Gheeraert, C. ; Firmin, F. ; Ploton, M. ; Kretova, M. ; Palierne, G. ; Staels, B. ; Barath, P. ; Talianidis, I. ; Lefebvre, P. ; Eeckhoute, J. ; Salbert, G.
Inactivation of the Nuclear Orphan Receptor COUP-TFII by Small Chemicals.
ACS Chem. Biol. 12, 654-663 (2017)
Calvo-Lerma, J. ; Martinez Jimenez, C.P. ; Lázaro-Ramos, J.P. ; Andrés, A. ; Crespo-Escobar, P. ; Stav, E. ; Schauber, C. ; Pannese, L. ; Hulst, J.M. ; Suárez, L. ; Colombo, C. ; Barreto, C. ; de Boeck, K. ; Ribes-Koninckx, C.
Innovative approach for self-management and social welfare of children with cystic fibrosis in Europe: development, validation and implementation of an mHealth tool (MyCyFAPP).
BMJ Open 7:e014931 (2017)
2016
Martinez Jimenez, C.P. ; Odom, D.T.
The mechanisms shaping the single-cell transcriptional landscape.
Curr. Opin. Genet. Dev. 37, 27-35 (2016)
2015
Martinez Jimenez, C.P. ; Sandoval, J.
Epigenetic crosstalk: a molecular language in human metabolic disorders.
Front. Biosci. 7, 46-57 (2015)
2014
Vicente-Muñoz, S. ; Romero, P. ; Magraner-Pardo, L. ; Martinez Jimenez, C.P. ; Tordera, V. ; Pamblanco, M.
Comprehensive analysis of interacting proteins and genome-wide location studies of the Sas3-dependent NuA3 histone acetyltransferase complex.
FEBS Open Bio 4, 996-1006 (2014)
2011
Molina-Navarro, M.M. ; Martinez Jimenez, C.P. ; Rodriguez-Navarro, S.
Transcriptional elongation and mRNA export are coregulated processes.
Genet. Res. Int. 2011:652461 (2011)
2010
Schmidt, D. ; Wilson, M.D. ; Ballester, B. ; Schwalie, P.C. ; Brown, G.D. ; Marshall, A. ; Kutter, C. ; Watt, S. ; Martinez Jimenez, C.P. ; Mackay, S. ; Talianidis, I. ; Flicek, P. ; Odom, D.T.
Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor binding.
Science 328, 1036-1040 (2010)
Martinez Jimenez, C.P. ; Kyrmizi, I. ; Cardot, P. ; Gonzalez, F.J. ; Talianidis, I.
Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism.
Mol. Cell. Biol. 30, 565-577 (2010)
2008
Tatarakis, A. ; Margaritis, T. ; Martinez Jimenez, C.P. ; Kouskouti, A. ; Mohan, W.S. ; Haroniti, A. ; Kafetzopoulos, D. ; Tora, L. ; Talianidis, I.
Dominant and redundant functions of TFIID involved in the regulation of hepatic genes.
Mol. Cell 31, 531-53 (2008)
2007
Martinez Jimenez, C.P. ; Jover, R. ; Donato, M.T. ; Castell, J.V. ; Gómez-Lechón, M.J.
Transcriptional regulation and expression of CYP3A4 in hepatocytes.
Curr. Drug Metab. 8, 185-194 (2007)
2006
Martinez Jimenez, C.P. ; Castell, J.V. ; Gómez-Lechón, M.J. ; Jover, R.
Transcriptional activation of CYP2C9, CYP1A1, and CYP1A2 by hepatocyte nuclear factor 4alpha requires coactivators peroxisomal proliferator activated receptor-gamma coactivator 1alpha and steroid receptor coactivator 1.
Mol. Pharmacol. 70, 1681-1692 (2006)
Martinez Jimenez, C.P. ; Gómez-Lechón, M.J. ; Castell, J.V. ; Jover, R.
Underexpressed coactivators PGC1alpha and SRC1 impair hepatocyte nuclear factor 4 alpha function and promote dedifferentiation in human hepatoma cells.
J. Biol. Chem. 281, 29840-29849 (2006)
Castell, J.V. ; Jover, R. ; Martinez Jimenez, C.P. ; Gómez-Lechón, M.J.
Hepatocyte cell lines: their use, scope and limitations in drug metabolism studies.
Expert Opin. Drug Metab. Toxicol. 2, 183-212 (2006)
2005
Martinez Jimenez, C.P. ; Gómez-Lechón, M.J. ; von Castell, J. ; Jover, R.
Engineering human hepatoma cells with key transcription factors to generate metabolically competent hepatic models.
ALTEX, 435-440 (2005)
Martinez Jimenez, C.P. ; Gómez-Lechón, M.J. ; Castell, J.V. ; Jover, R.
Transcriptional regulation of the human hepatic CYP3A4: Identification of a new distal enhancer region responsive to CCAAT/enhancer-binding protein beta isoforms (liver activating protein and liver inhibitory protein).
Mol. Pharmacol. 67, 2088-2101 (2005)
Handschin, C. ; Gnerre, C. ; Fraser, D.J. ; Martinez Jimenez, C.P. ; Jover, R. ; Meyer, U.A.
Species-specific mechanisms for cholesterol 7α -hydroxylase (CYP7A1) regulation by drugs and bile acids.
Arch. Biochem. Biophys. 434, 75-85 (2005)
2004
Martinez Jimenez, C.P. ; Jover, R. ; Gómez-Lechón, M.J. ; Castell, J.V.
Can hepatoma cell lines be redifferentiated to be used in drug metabolism studies?
In:. 2004. 65-74 (ATLA-Altern. Lab. Anim. ; 32 Suppl 1A)