Biomedicine
HPC embraces new technologies, which promise to reveal unprecedented insights into biological systems, during normal development, homeostasis and disease. Our approaches include high-resolution-imaging, single cell multi-omics, microfluidic-, ‘organ on chip’, nano-scale interactions and atomic resolution cryo-EM to accurately quantify biological systems in health in disease. Overall, HPC technologies are geared towards novel solutions that improve personalised prevention and inform new diagnostics and therapies.
Principal Investigators
HPC Principal Investigators are outstanding scientists with a proven track record in their respective fields and the ambition to make a difference in biomedicine, harnessing engineering and informatics tools. They are interdisciplinary by nature, highly collaborative, and committed to drive a globally competitive research program.
Boyan Bonev
3D Genome & Molecular Neurobiology
Boyan's team deciphers the genetic and epigenetic blueprints of brain development and evolution, thereby unravelling new paradigms at the interplay of transcription factors, chromatin topology and the control of gene expression in vivo.
Celia P. Martinez Jimenez
Molecular Ageing
Celia's team applies single-cell approaches to interrogate molecular features as predictor of molecular age. The assessment of intra-organ cell-to-cell variability will instruct precision diagnostics and personalized treatments.
Matthias Meier
Bioengineering and Microfluidics
Matthias' team advances the microfluidic organ-on-chip technology to characterize biomolecules and their functional interactions on the single cell level and in the context of whole organs.